The transformation of the fashion industry, along with changes in cultural and social patterns, has shifted the role of fashion-related spaces from merely display-oriented environments to platforms for social interaction, spatial experience, and the representation of cultural identity. Despite the rich potential of Iranian architecture and clothing traditions, many fashion houses in Iran lack a coherent spatial identity and experience-oriented quality. Therefore, the present study aims to identify and explain the factors influencing the interior design of Iranian fashion houses with an interaction-oriented approach toward the fashion community. This research is applied in terms of purpose and descriptive-analytical in terms of methodology. The required data were collected through library-based and field studies. Data analysis was conducted using Statistical Package for the Social Sciences (SPSS) software, employing statistical techniques including Cronbach’s alpha, Pearson correlation coefficient, and multiple regression analysis. The findings indicate that interactive and human-centered design has the greatest impact on the quality of fashion house spaces. In addition, spatial quality, lighting, material selection, color schemes, and the incorporation of elements derived from Iranian architecture and clothing play a significant role in enhancing users’ spatial experiences. The results further reveal that integrating the identity-related characteristics of Iranian clothing into the interior design of fashion houses can contribute to the creation of distinctive, contemporary, and user-centered environments that respond effectively to the needs of both users and the fashion community.